Study finds reservoir of hidden HIV bigger than once thought

In fact it was reported as being 60-times greater!

See full article:

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure, Cell, 24 Oct 2013; vol 155" pp 540-551


  • A total of 1.7% of noninduced HIV-1 proviruses have intact genomes and LTR function
  • Reconstructed intact noninduced proviruses are replication competent
  • They are integrated into transcription units and have no CpG methylation in the LTR
  • The size of the latent reservoir for HIV-1 may be underestimated by 60-fold